Publications récentes
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26 mars 2026 Extracellular vesicles from aged individuals trigger mitochondrial dysfunction in haematopoietic progenitor cells.
Grenier-Pleau IJ, Kaur J, Wells CJ, Vermeulen M, Slobodyanyuk M, Holmes SM, Bonneil E, Hall C, Beaulieu J, Hosseini M, Chan SM, Dick SA, Knapp D, Tyryshkin K, Postovit LM, Thibault P, Rudan JF, Mann S, Craig AW, Reimand J, Chan EYW, Abraham SA
Haematologica 2026-03-26 ; -
19 février 2026 The deubiquitinase USP17 regulates the expression and activity of the oncogenic driver β-catenin in colorectal cancer.
Acevedo M, Dô F, El-Mortada F, Tanguay PL, Voisin L, Houles T, Lavoie G, Allard D, Roux PP, Stagg J, Doré S, Walsh L, Fourtounis J, Bonneil E, Meloche S, Servant MJ
Oncogene 2026-02-19 ; -
17 février 2026 From Lead to Clinical Candidate: Discovery of BMS-986331 as a Potent and Selective N-Formyl Peptide Receptor 2 Agonist.
Shirude PS, Cheney D, Chattopadhyay AK, Seshadri B, Baligar V, Rachamreddy C, Madduri S, Anjanappa P, Viet A, Valente MN, Rossi K, Abousleiman M, Hsu MY, Everlof G, Gali V, Sun Y, Allocco J, Zhang R, St-Onge S, Lupisella J, Chen XQ, Sarodaya S, Ravindran MS, Tagore DM, Nagar J, Dudhgaonkar S, Putlur S, Héroux M, Bouvier M, Wexler RR, Dierks E, Garcia RA, Kick EK, Wurtz NR
J Med Chem 2026-02-17 ; -
30 janvier 2026 A Chemical-Genetic Interaction Matrix Reveals Drug Mechanism and Genetic Architecture.
Coulombe-Huntington J, Bertomeu T, Huard C, Chatr-Aryamontri A, St-Cyr DJ, Sánchez-Osuna M, Papadopoli D, Normandin K, Paydar M, McLaughlan S, St-Denis C, Zhang L, Say H, Palou R, Stark C, Breitkreutz BJ, van der Sloot AM, Manohar S, Lavoie H, Borden K, Raught B, D'Amours D, Sicheri F, Verreault A, Mader S, Meloche S, Therrien M, Thibault P, Wilhelm B, Dirks PB, Aitchison JD, Patton E, King RW, Roux PP, Sauvageau G, Hoang T, Marinier A, Harrington L, Kwok B, Archambault V, Topisirovic I, Tyers M
bioRxiv 2026-01-30 ;