199 résultats
Immunogenicity of Non-Mutated Ovarian Cancer-Specific Antigens.
Hesnard L, Thériault C, Cahuzac M, Durette C, Vincent K, Hardy MP, Lanoix J, Lavallée GO, Humeau J, Thibault P, Perreault C
Curr Oncol
2024-05-30
;31(
6
):3099-3121.
Transposable elements regulate thymus development and function.
Larouche JD, Laumont CM, Trofimov A, Vincent K, Hesnard L, Brochu S, Côté C, Humeau JF, Bonneil E, Lanoix J, Durette C, Gendron P, Laverdure JP, Richie ER, Lemieux S, Thibault P, Perreault C
Elife
2024-04-18
;12:.
Autophagy degrades immunogenic endogenous retroelements induced by 5-azacytidine in acute myeloid leukemia.
Noronha N, Durette C, Cahuzac M, E Silva B, Courtois J, Humeau J, Sauvat A, Hardy MP, Vincent K, Laverdure JP, Lanoix J, Baron F, Thibault P, Perreault C, Ehx G
Leukemia
2024-04-16
;.
Breast cancer immunopeptidomes contain numerous shared tumor antigens.
Kina E, Laverdure JP, Durette C, Lanoix J, Courcelles M, Zhao Q, Apavaloaei A, Larouche JD, Hardy MP, Vincent K, Gendron P, Hesnard L, Thériault C, Ruiz Cuevas MV, Ehx G, Thibault P, Perreault C
J Clin Invest
2023-10-31
;.
Immunotargeting of a recurrent AML-specific neoantigen.
Apavaloaei A, Perreault C
Nat Cancer
2023-10-02
;.
BamQuery: a proteogenomic tool to explore the immunopeptidome and prioritize actionable tumor antigens.
Cuevas MVR, Hardy MP, Larouche JD, Apavaloaei A, Kina E, Vincent K, Gendron P, Laverdure JP, Durette C, Thibault P, Lemieux S, Perreault C, Ehx G
Genome Biol
2023-08-15
;24(
1
):188.
Introduction to the Special Issue: The Immunopeptidome.
Caron E, Perreault C
Semin Immunol
2023-06-19
;69:101798.
OpenCustomDB: Integration of Unannotated Open Reading Frames and Genetic Variants to Generate More Comprehensive Customized Protein Databases.
Guilloy N, Brunet MA, Leblanc S, Jacques JF, Hardy MP, Ehx G, Lanoix J, Thibault P, Perreault C, Roucou X
J Proteome Res
2023-03-24
;.
Identification of antigenic epitopes recognized by tumor infiltrating lymphocytes in high grade serous ovarian cancer by multi-omics profiling of the auto-antigen repertoire.
Millar DG, Yang SYC, Sayad A, Zhao Q, Nguyen LT, Warner K, Sangster AG, Nakatsugawa M, Murata K, Wang BX, Shaw P, Clarke B, Bernardini MQ, Pugh T, Thibault P, Hirano N, Perreault C, Ohashi PS
Cancer Immunol Immunother
2023-03-21
;.
Klf4 protects thymus integrity during late pregnancy.
Depoërs L, Dumont-Lagacé M, Trinh VQ, Houques C, Côté C, Larouche JD, Brochu S, Perreault C
Front Immunol
2023-01-01
;14:1016378.
Two types of human TCR differentially regulate reactivity to self and non-self antigens.
Trofimov A, Brouillard P, Larouche JD, Séguin J, Laverdure JP, Brasey A, Ehx G, Roy DC, Busque L, Lachance S, Lemieux S, Perreault C
iScience
2022-09-16
;25(
9
):104968.
Induced pluripotent stem cells display a distinct set of MHC I-associated peptides shared by human cancers.
Apavaloaei A, Hesnard L, Hardy MP, Benabdallah B, Ehx G, Thériault C, Laverdure JP, Durette C, Lanoix J, Courcelles M, Noronha N, Chauhan KD, Lemieux S, Beauséjour C, Bhatia M, Thibault P, Perreault C
Cell Rep
2022-08-16
;40(
7
):111241.
Immunopeptidomics: Reading the Immune Signal That Defines Self From Nonself.
Thibault P, Perreault C
Mol Cell Proteomics
2022-05-11
;21(
6
):100234.
Immunopeptidomic analyses of colorectal cancers with and without microsatellite instability.
Cleyle J, Hardy MP, Minati R, Courcelles M, Durette C, Lanoix J, Laverdure JP, Vincent K, Perreault C, Thibault P
Mol Cell Proteomics
2022-05-01
;21(
5
):100228.
Regulation of MHC Class I Expression in Lung Epithelial Cells during Inflammation.
Mathé J, Benhammadi M, Kobayashi KS, Brochu S, Perreault C
J Immunol
2022-03-01
;208(
5
):1021-1033.
CAMAP: Artificial neural networks unveil the role of codon arrangement in modulating MHC-I peptides presentation.
Daouda T, Dumont-Lagacé M, Feghaly A, Benslimane Y, Panes R, Courcelles M, Benhammadi M, Harrington L, Thibault P, Major F, Bengio Y, Gagnon E, Lemieux S, Perreault C
PLoS Comput Biol
2021-10-22
;17(
10
):e1009482.
PSMB11 regulates gene expression in cortical thymic epithelial cells.
Apavaloaei A, Laverdure JP, Perreault C
Cell Rep
2021-09-07
;36(
10
):109546.
Beneficial autoimmunity improves cancer prognosis.
Zitvogel L, Perreault C, Finn OJ, Kroemer G
Nat Rev Clin Oncol
2021-09-01
;18(
9
):591-602.
A bacterium-derived, cancer-associated immunopeptidome.
Perreault C, Thibault P, Kroemer G
Oncoimmunology
2021-05-03
;10(
1
):1918373.
Atypical acute myeloid leukemia-specific transcripts generate shared and immunogenic MHC class-I-associated epitopes.
Ehx G, Larouche JD, Durette C, Laverdure JP, Hesnard L, Vincent K, Hardy MP, Thériault C, Rulleau C, Lanoix J, Bonneil E, Feghaly A, Apavaloaei A, Noronha N, Laumont CM, Delisle JS, Vago L, Hébert J, Sauvageau G, Lemieux S, Thibault P, Perreault C
Immunity
2021-04-13
;54(
4
):737-752.e10.
Most non-canonical proteins uniquely populate the proteome or immunopeptidome.
Ruiz Cuevas MV, Hardy MP, Hollý J, Bonneil E, Durette C, Courcelles M, Lanoix J, Côté C, Staudt LM, Lemieux S, Thibault P, Perreault C, Yewdell JW
Cell Rep
2021-03-09
;34(
10
):108815.
UM171-Expanded Cord Blood Transplants Support Robust T Cell Reconstitution with Low Rates of Severe Infections.
Dumont-Lagacé M, Li Q, Tanguay M, Chagraoui J, Kientega T, Cardin GB, Brasey A, Trofimov A, Carli C, Ahmad I, Bambace NM, Bernard L, Kiss TL, Roy J, Roy DC, Lemieux S, Perreault C, Rodier F, Dufresne SF, Busque L, Lachance S, Sauvageau G, Cohen S, Delisle JS
Transplant Cell Ther
2021-01-01
;27(
1
):76.e1-76.e9.
A Roadmap Toward the Definition of Actionable Tumor-Specific Antigens.
Minati R, Perreault C, Thibault P
Front Immunol
2020-12-03
;11:583287.
Major multilevel molecular divergence between THP-1 cells from different biorepositories.
Noronha N, Ehx G, Meunier MC, Laverdure JP, Thériault C, Perreault C
Int. J. Cancer
2020-10-01
;147(
7
):2000-2006.
The Origin and Immune Recognition of Tumor-Specific Antigens.
Apavaloaei A, Hardy MP, Thibault P, Perreault C
Cancers (Basel)
2020-09-12
;12(
9
):.
IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells.
Benhammadi M, Mathé J, Dumont-Lagacé M, Kobayashi KS, Gaboury L, Brochu S, Perreault C
J. Immunol.
2020-09-01
;205(
5
):1268-1280.
Apoptotic exosome-like vesicles regulate endothelial gene expression, inflammatory signaling, and function through the NF-κB signaling pathway.
Migneault F, Dieudé M, Turgeon J, Beillevaire D, Hardy MP, Brodeur A, Thibodeau N, Perreault C, Hébert MJ
Sci Rep
2020-07-28
;10(
1
):12562.
Extending the Comprehensiveness of Immunopeptidome Analyses Using Isobaric Peptide Labeling.
Pfammatter S, Bonneil E, Lanoix J, Vincent K, Hardy MP, Courcelles M, Perreault C, Thibault P
Anal. Chem.
2020-07-07
;92(
13
):9194-9204.
Factorized embeddings learns rich and biologically meaningful embedding spaces using factorized tensor decomposition.
Trofimov A, Cohen JP, Bengio Y, Perreault C, Lemieux S
Bioinformatics
2020-07-01
;36(
Supplement_1
):i417-i426.
Widespread and tissue-specific expression of endogenous retroelements in human somatic tissues.
Larouche JD, Trofimov A, Hesnard L, Ehx G, Zhao Q, Vincent K, Durette C, Gendron P, Laverdure JP, Bonneil E, Côté C, Lemieux S, Thibault P, Perreault C
Genome Med
2020-04-28
;12(
1
):40.
Proteogenomics Uncovers a Vast Repertoire of Shared Tumor-Specific Antigens in Ovarian Cancer.
Zhao Q, Laverdure JP, Lanoix J, Durette C, Côté C, Bonneil E, Laumont CM, Gendron P, Vincent K, Courcelles M, Lemieux S, Millar DG, Ohashi PS, Thibault P, Perreault C
Cancer Immunol Res
2020-04-03
;8(
4
):544-555.
MAPDP: A Cloud-Based Computational Platform for Immunopeptidomics Analyses.
Courcelles M, Durette C, Daouda T, Laverdure JP, Vincent K, Lemieux S, Perreault C, Thibault P
J. Proteome Res.
2020-04-03
;19(
4
):1873-1881.
Qualitative Changes in Cortical Thymic Epithelial Cells Drive Postpartum Thymic Regeneration.
Dumont-Lagacé M, Daouda T, Depoërs L, Zumer J, Benslimane Y, Brochu S, Harrington L, Lemieux S, Perreault C
Front Immunol
2020-02-11
;10:3118.
The Genomic Landscape of Antigenic Targets for T Cell-Based Leukemia Immunotherapy.
Hardy MP, Vincent K, Perreault C
Front Immunol
2020-01-13
;10:2934.
Allodepleted T-cell immunotherapy after haploidentical haematopoietic stem cell transplantation without severe acute graft-versus-host disease (GVHD) in the absence of GVHD prophylaxis.
Roy DC, Lachance S, Cohen S, Delisle JS, Kiss T, Sauvageau G, Busque L, Ahmad I, Bernard L, Bambace N, Boumédine RS, Guertin MC, Rezvani K, Mielke S, Perreault C, Roy J
Br. J. Haematol.
2019-09-01
;186(
5
):754-766.
Apoptotic endothelial cells release small extracellular vesicles loaded with immunostimulatory viral-like RNAs.
Hardy MP, Audemard É, Migneault F, Feghaly A, Brochu S, Gendron P, Boilard É, Major F, Dieudé M, Hébert MJ, Perreault C
Sci Rep
2019-05-10
;9(
1
):7203.
Discovery and characterization of actionable tumor antigens.
Ehx G, Perreault C
Genome Med
2019-04-30
;11(
1
):29.
PSMB11 Orchestrates the Development of CD4 and CD8 Thymocytes via Regulation of Gene Expression in Cortical Thymic Epithelial Cells.
Apavaloaei A, Brochu S, Dong M, Rouette A, Hardy MP, Villafano G, Murata S, Melichar HJ, Perreault C
J. Immunol.
2018-12-19
;.
Noncoding regions are the main source of targetable tumor-specific antigens.
Laumont CM, Vincent K, Hesnard L, Audemard É, Bonneil É, Laverdure JP, Gendron P, Courcelles M, Hardy MP, Côté C, Durette C, St-Pierre C, Benhammadi M, Lanoix J, Vobecky S, Haddad E, Lemieux S, Thibault P, Perreault C
Sci Transl Med
2018-12-05
;10(
470
):.
Comparison of the MHC I Immunopeptidome Repertoire of B-Cell Lymphoblasts Using Two Isolation Methods.
Lanoix J, Durette C, Courcelles M, Cossette É, Comtois-Marotte S, Hardy MP, Côté C, Perreault C, Thibault P
Proteomics
2018-06-01
;18(
12
):e1700251.
Exploiting non-canonical translation to identify new targets for T cell-based cancer immunotherapy.
Laumont CM, Perreault C
Cell. Mol. Life Sci.
2018-02-01
;75(
4
):607-621.
The SysteMHC Atlas project.
Shao W, Pedrioli PGA, Wolski W, Scurtescu C, Schmid E, Vizcaíno JA, Courcelles M, Schuster H, Kowalewski D, Marino F, Arlehamn CSL, Vaughan K, Peters B, Sette A, Ottenhoff THM, Meijgaarden KE, Nieuwenhuizen N, Kaufmann SHE, Schlapbach R, Castle JC, Nesvizhskii AI, Nielsen M, Deutsch EW, Campbell DS, Moritz RL, Zubarev RA, Ytterberg AJ, Purcell AW, Marcilla M, Paradela A, Wang Q, Costello CE, Ternette N, van Veelen PA, van Els CACM, Heck AJR, de Souza GA, Sollid LM, Admon A, Stevanovic S, Rammensee HG, Thibault P, Perreault C, Bassani-Sternberg M, Aebersold R, Caron E
Nucleic Acids Res.
2018-01-04
;46(
D1
):D1237-D1247.
Detection of Quiescent Radioresistant Epithelial Progenitors in the Adult Thymus.
Dumont-Lagacé M, Gerbe H, Daouda T, Laverdure JP, Brochu S, Lemieux S, Gagnon E, Perreault C
Front Immunol
2017-12-05
;8:1717.
Immunoproteasomes Control the Homeostasis of Medullary Thymic Epithelial Cells by Alleviating Proteotoxic Stress.
St-Pierre C, Morgand E, Benhammadi M, Rouette A, Hardy MP, Gaboury L, Perreault C
Cell Rep
2017-11-28
;21(
9
):2558-2570.
Immunogenic stress and death of cancer cells: Contribution of antigenicity vs adjuvanticity to immunosurveillance.
Bloy N, Garcia P, Laumont CM, Pitt JM, Sistigu A, Stoll G, Yamazaki T, Bonneil E, Buqué A, Humeau J, Drijfhout JW, Meurice G, Walter S, Fritsche J, Weinschenk T, Rammensee HG, Melief C, Thibault P, Perreault C, Pol J, Zitvogel L, Senovilla L, Kroemer G
Immunol. Rev.
2017-11-01
;280(
1
):165-174.
An Unbiased Linkage Approach Reveals That the p53 Pathway Is Coupled to NK Cell Maturation.
Collin R, St-Pierre C, Guilbault L, Mullins-Dansereau V, Policheni A, Guimont-Desrochers F, Pelletier AN, Gray DH, Drobetsky E, Perreault C, Hillhouse EE, Lesage S
J. Immunol.
2017-08-15
;199(
4
):1490-1504.
Major vs minor histocompatibility antigens.
Roy DC, Perreault C
Blood
2017-02-09
;129(
6
):664-666.
MHC class I-associated peptides derive from selective regions of the human genome.
Pearson H, Daouda T, Granados DP, Durette C, Bonneil E, Courcelles M, Rodenbrock A, Laverdure JP, Côté C, Mader S, Lemieux S, Thibault P, Perreault C
J. Clin. Invest.
2016-12-01
;126(
12
):4690-4701.
Expression of immunoproteasome genes is regulated by cell-intrinsic and -extrinsic factors in human cancers.
Rouette A, Trofimov A, Haberl D, Boucher G, Lavallée VP, D'Angelo G, Hébert J, Sauvageau G, Lemieux S, Perreault C
Sci Rep
2016-09-23
;6:34019.
ERAAP Shapes the Peptidome Associated with Classical and Nonclassical MHC Class I Molecules.
Nagarajan NA, de Verteuil DA, Sriranganadane D, Yahyaoui W, Thibault P, Perreault C, Shastri N
J. Immunol.
2016-08-15
;197(
4
):1035-43.