Understanding the protective role of the immune system against cancers and development of immuno-therapeutic approaches. Characterization of the blood stem cells and their derivatives and study of the genesis of hematological cancers.
Principal Investigators
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Etienne Gagnon
Cancer Immunobiology
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Trang Hoang
Hematopoiesis and Leukemia
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David Knapp
Cellular Engineering
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Philippe P. Roux
Cell Signaling and Proteomics
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Claude Perreault
Immunobiology
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Brian Wilhelm
High-Throughput Genomics
Publications
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July 2, 2024 Genetic deletion of JAM-C in pre-leukemic cells rewires leukemic stem cell gene expression program in AML.
Grenier JMP, Testut C, Bal M, Bardin F, De Grandis M, Gelsi-Boyer V, Vernerny J, Delahaye MC, Granjeaud S, Zemmour C, Spinella JF, Chavakis T, Mancini SJ, Boher JM, Hébert J, Sauvageau G, Vey N, Schwaller J, Hospital MA, Fauriat C, Aurrand-Lions MA
Blood Adv 2024-07-02 ; -
June 20, 2024 Protein arginine methyltransferase 2 controls inflammatory signaling in acute myeloid leukemia.
Sauter C, Morin T, Guidez F, Simonet J, Fournier C, Row C, Masnikov D, Pernon B, Largeot A, Aznague A, Hérault Y, Sauvageau G, Maynadié M, Callanan M, Bastie JN, Aucagne R, Delva L
Commun Biol 2024-06-20 ;7( 1 ):753 - See all publications