Principal Investigator

Claude Perreault

Immunobiology

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A hematologist and immunogeneticist by training, Claude Perreault has been a senior researcher at the Institute since 2005, where he heads the immunobiology research laboratory. He is a full professor in the Faculté de médecine à l’Université de Montréal and practiced as a clinician until 2018 at Maisonneuve-Rosemont Hospital, where he created the histocompatibility laboratory and founded the bone marrow transplant unit.

A member of the Académie canadienne des sciences de la santé, Claude Perreault received the Acfas Léo-Pariseau Award (2011), the Michel-Sarrazin Award (2015) from the Club de recherches cliniques du Québec, and the Bernhard Cinader de la Société canadienne d’immunologie award (2017)

Principal Investigator, Immunobiology Research Unit, IRIC

Professor, Department of Medicine, Faculty of Medicine, Université de Montréal

Research unit on immunobiology

Marcelle-Coutu Pavilion, 1306-9

Phone (office)
(514) 343-6126
Fax
(514) 343-7780
Email
claude.perreault@umontreal.ca
Apply for a M.Sc. or a Ph.D.

Immunobiology

Claude Perreault and his team study the cells governing the function of the immune system, called “T lymphocytes”, in order to understand and improve the function of the immune system. One of the aims of his research is to create a cancer vaccine and prevent the ageing of the immune system.

Discover the research unit View the research team

Research topics

Publications

  • December 12, 2025

    CDK4/6 inhibition reprograms the breast cancer immunopeptidome via Rb-dependent chromatin and transcriptomic remodeling.

    Minati R, Cahuzac M, Perrault J, Lullier V, Apavaloaei A, Bonneil E, Courcelles M, Lanoix J, Kina E, Perreault C, Thibault P
    Cell Rep 2025-12-12 ;44( 12 ):116676

  • September 18, 2025

    Transgenic inducible MHC I overexpression in mouse alveolar type 2 cells.

    Mathé J, Brochu S, Saba-El-Leil MK, Coté C, Karia A, Harton S, Perreault C
    Transgenic Res 2025-09-18 ;34( 1 ):43

  • May 22, 2025

    Tumor antigens preferentially derive from unmutated genomic sequences in melanoma and non-small cell lung cancer.

    Apavaloaei A, Zhao Q, Hesnard L, Cahuzac M, Durette C, Larouche JD, Hardy MP, Vincent K, Brochu S, Laverdure JP, Lanoix J, Courcelles M, Gendron P, Lajoie M, Ruiz Cuevas MV, Kina E, Perrault J, Humeau J, Ehx G, Lemieux S, Watson IR, Speiser DE, Bassani-Sternberg M, Thibault P, Perreault C
    Nat Cancer 2025-05-22 ;

  • October 9, 2024

    The cryptic immunopeptidome in health and disease.

    Kina E, Larouche JD, Thibault P, Perreault C
    Trends Genet 2024-10-09 ;

  • See all publications

Awards and distinctions

  • Till and McCulloch Lectureship Award, Canadian Blood and Marrow Transplant Group, 2019

  • Bernhard Cinader Award, Canadian Society for Immunology, 2017

  • Professor “au mérite de carrière” - Department of Medicine, Université de Montréal, 2016

  • Michel-Sarrazin Award, Club de recherches cliniques du Québec, 2015

  • Distinguished member, Association des Médecins Hématologues et Oncologues du Québec, 2013

  • Léo-Pariseau Award, Association francophone pour le savoir, 2011

  • Fellow, Canadian Academy of Health Sciences, 2010

  • Canada Research Chair in Immunobiology, 2004–2018

  • Murray Margarit Memorial Award, Leukemia and Lymphoma Society of Canada, 2009

    • See all awards