Research field

Computational Analysis & Modeling

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Development of informatics tools for the analysis and interpretation of large biological datasets including genomics, proteomics and structural biology data. Modeling of complex biological systems.

Principal Investigators

  • Delphine Bouilly

    Design and Application of Electronic Nanobiosensors

  • Louis Gaboury

    Histology and Molecular Pathology

  • Jean-Claude Labbé

    Cell Division and Differentiation

  • Sébastien Lemieux

    Functional and Structural Bioinformatics

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • August 21, 2024

    A Novel Confocal Scanning Protein-Protein Interaction Assay (PPI-CONA) Reveals Exceptional Selectivity and Specificity of CC0651, a Small Molecule Binding Enhancer of the Weak Interaction between the E2 Ubiquitin-Conjugating Enzyme CDC34A and Ubiquitin.

    Koszela J, Pham NT, Shave S, St-Cyr D, Ceccarelli DF, Orlicky S, Marinier A, Sicheri F, Tyers M, Auer M
    Bioconjug Chem 2024-08-21 ;

  • July 8, 2024

    Long-term severe hypoxia adaptation induces non-canonical EMT and a novel Wilms Tumor 1 (WT1) isoform.

    Quenneville J, Feghaly A, Tual M, Thomas K, Major F, Gagnon E
    Cancer Gene Ther 2024-07-08 ;

  • July 7, 2024

    Role of the V2R-βarrestin-Gβγ complex in promoting G protein translocation to endosomes.

    Sokrat B, Nguyen AH, Thomsen ARB, Huang LY, Kobayashi H, Kahsai AW, Kim J, Ho BX, Ma S, Little J, Ehrhart C, Pyne I, Hammond E, Bouvier M
    Commun Biol 2024-07-07 ;7( 1 ):826

  • See all publications