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  • November 5, 2023

    The eukaryotic translation initiation factor eIF4E unexpectedly acts in splicing thereby coupling mRNA processing with translation: eIF4E induces widescale splicing reprogramming providing system-wide connectivity between splicing, nuclear mRNA export and translation.

    Borden K
    Bioessays 2023-11-05 ;e2300145

  • November 2, 2023

    p38 MAPK signaling in chronic obstructive pulmonary disease pathogenesis and inhibitor therapeutics.

    Ahmadi A, Ahrari S, Salimian J, Salehi Z, Karimi M, Emamvirdizadeh A, Jamalkandi SA, Ghanei M
    Cell Commun Signal 2023-11-02 ;21( 1 ):314

  • October 31, 2023

    Breast cancer immunopeptidomes contain numerous shared tumor antigens.

    Kina E, Laverdure JP, Durette C, Lanoix J, Courcelles M, Zhao Q, Apavaloaei A, Larouche JD, Hardy MP, Vincent K, Gendron P, Hesnard L, Thériault C, Ruiz Cuevas MV, Ehx G, Thibault P, Perreault C
    J Clin Invest 2023-10-31 ;

  • October 20, 2023

    The human leukemic oncogene MLL-AF4 promotes hyperplastic growth of hematopoietic tissues in Drosophila larvae.

    Johannessen JA, Formica M, Haukeland ALC, Bråthen NR, Al Outa A, Aarsund M, Therrien M, Enserink JM, Knævelsrud H
    iScience 2023-10-20 ;26( 10 ):107726

  • October 17, 2023

    A renaissance for YES in cancer.

    Lapouge M, Meloche S
    Oncogene 2023-10-17 ;

  • October 9, 2023

    GLP-1R signaling neighborhoods associate with the susceptibility to adverse drug reactions of incretin mimetics.

    Wright SC, Motso A, Koutsilieri S, Beusch CM, Sabatier P, Berghella A, Blondel-Tepaz E, Mangenot K, Pittarokoilis I, Sismanoglou DC, Le Gouill C, Olsen JV, Zubarev RA, Lambert NA, Hauser AS, Bouvier M, Lauschke VM
    Nat Commun 2023-10-09 ;14( 1 ):6243

  • October 6, 2023

    XPO1 enables adaptive regulation of mRNA export required for genotoxic stress tolerance in cancer cells.

    Marullo R, Rutherford SC, Revuelta MV, Zamponi N, Culijkovic B, Kotlov N, Di Siervi N, Lara-Garcia J, Allan JN, Ruan J, Furman RR, Chen Z, Shore TB, Phillips AA, Mayer S, Hsu J, van Besien K, Leonard JP, Borden K, Inghirami G, Martin P, Cerchietti L
    Cancer Res 2023-10-06 ;

  • October 4, 2023

    RECOVER identifies synergistic drug combinations in vitro through sequential model optimization.

    Bertin P, Rector-Brooks J, Sharma D, Gaudelet T, Anighoro A, Gross T, Martínez-Peña F, Tang EL, Suraj MS, Regep C, Hayter JBR, Korablyov M, Valiante N, van der Sloot A, Tyers M, Roberts CES, Bronstein MM, Lairson LL, Taylor-King JP, Bengio Y
    Cell Rep Methods 2023-10-04 ;3( 10 ):100599

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