Latest publications
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October 1, 2023 Human GLP1R variants affecting GLP1R cell surface expression are associated with impaired glucose control and increased adiposity.
Gao W, Liu L, Huh E, Gbahou F, Cecon E, Oshima M, Houzé L, Katsonis P, Hegron A, Fan Z, Hou G, Charpentier G, Boissel M, Derhourhi M, Marre M, Balkau B, Froguel P, Scharfmann R, Lichtarge O, Dam J, Bonnefond A, Liu J, Jockers R
Nat Metab 2023-10-01 ;5( 10 ):1673-1684 -
September 27, 2023 Gαs is dispensable for β-arrestin coupling but dictates GRK selectivity and is predominant for gene expression regulation by β2-adrenergic receptor.
Burghi V, Paradis JS, Officer A, Adame Garcia S, Wu X, Matthees ES, Barsi-Rhyne B, Ramms DJ, Clubb L, Acosta M, Tamayo P, Bouvier M, Inoue A, von Zastrow M, Hoffmann C, Gutkind JS
J Biol Chem 2023-09-27 ;105293 -
September 22, 2023 -
September 20, 2023 CBFA2T3::GLIS2 Pediatric Acute Megakaryoblastic Leukemia is Sensitive to BCL-XL Inhibition by Navitoclax and DT2216.
Gress V, Roussy M, Boulianne L, Bilodeau M, Cardin S, El-Hachem N, Lisi V, Khakipoor B, Rouette A, Farah A, Théret L, Aubert L, Fatima F, Audemard E, Thibault P, Bonneil E, Chagraoui J, Laramée L, Gendron P, Jouan L, Jammali S, Paré B, Simpson SM, Tran TH, Duval M, Teira P, Bittencourt H, Santiago R, Barabé F, Sauvageau G, Smith M, Hébert J, Roux PP, Gruber TA, Lavallée VP, Wilhelm B, Cellot S
Blood Adv 2023-09-20 ; -
September 12, 2023 Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption.
Kho I, Demina EP, Pan X, Londono I, Cairo CW, Sturiale L, Palmigiano A, Messina A, Garozzo D, Ung RV, Mac-Way F, Bonneil E, Thibault P, Lemaire M, Morales CR, Pshezhetsky AV
JCI Insight 2023-09-12 ;