Identification of biological markers of cancer and development of new diagnostic tools. Development of new targeted therapies and innovative drugs against cancer.
Principal Investigators
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Delphine Bouilly
Design and Application of Electronic Nanobiosensors
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Michel Bouvier
Molecular Pharmacology
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Sébastien Carréno
Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility
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Louis Gaboury
Histology and Molecular Pathology
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Etienne Gagnon
Cancer Immunobiology
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Trang Hoang
Hematopoiesis and Leukemia
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Julie Lessard
Chromatin Structure and Stem Cell Biology
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Sylvie Mader
Molecular Targeting in Breast Cancer Treatment
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François Major
RNA Engineering
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Anne Marinier
Drug Discovery
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Sylvain Meloche
Signalling and Cell Growth
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Philippe P. Roux
Cell Signaling and Proteomics
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Claude Perreault
Immunobiology
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Guy Sauvageau
Molecular Genetics of Stem Cells
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Marc Therrien
Intracellular Signalling
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Pierre Thibault
Proteomics and Mass Spectrometry
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Vincent Quoc-Huy Trinh
Digital Histology and Advanced Pathology
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Brian Wilhelm
High-Throughput Genomics
Publications
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August 21, 2024 A Novel Confocal Scanning Protein-Protein Interaction Assay (PPI-CONA) Reveals Exceptional Selectivity and Specificity of CC0651, a Small Molecule Binding Enhancer of the Weak Interaction between the E2 Ubiquitin-Conjugating Enzyme CDC34A and Ubiquitin.
Koszela J, Pham NT, Shave S, St-Cyr D, Ceccarelli DF, Orlicky S, Marinier A, Sicheri F, Tyers M, Auer M
Bioconjug Chem 2024-08-21 ; -
July 18, 2024 Ezrin, radixin, and moesin are dispensable for macrophage migration and cellular cortex mechanics.
Verdys P, Rey Barroso J, Girel A, Vermeil J, Bergert M, Sanchez T, Métais A, Mangeat T, Bellard E, Bigot C, Astarie-Dequeker C, Labrousse A, Girard JP, Maridonneau-Parini I, Vérollet C, Lagarrigue F, Diz-Muñoz A, Heuvingh J, Piel M, du Roure O, Le Cabec V, Carréno S, Poincloux R
EMBO J 2024-07-18 ; - See all publications