Research field

Genomics & Epigenetics

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Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Lemieux

    Functional and Structural Bioinformatics

  • Julie Lessard

    Chromatin Structure and Stem Cell Biology

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Guy Sauvageau

    Molecular Genetics of Stem Cells

  • Vincent Quoc-Huy Trinh

    Digital Histology and Advanced Pathology

  • Brian Wilhelm

    High-Throughput Genomics

Publications

  • July 25, 2024

    Syngeneic mouse model of YES-driven metastatic and proliferative hepatocellular carcinoma.

    Voisin L, Lapouge M, Saba-El-Leil MK, Gombos M, Javary J, Trinh VQ, Meloche S
    Dis Model Mech 2024-07-25 ;17( 7 ):

  • July 8, 2024

    Long-term severe hypoxia adaptation induces non-canonical EMT and a novel Wilms Tumor 1 (WT1) isoform.

    Quenneville J, Feghaly A, Tual M, Thomas K, Major F, Gagnon E
    Cancer Gene Ther 2024-07-08 ;

  • July 2, 2024

    Genetic deletion of JAM-C in pre-leukemic cells rewires leukemic stem cell gene expression program in AML.

    Grenier JMP, Testut C, Bal M, Bardin F, De Grandis M, Gelsi-Boyer V, Vernerny J, Delahaye MC, Granjeaud S, Zemmour C, Spinella JF, Chavakis T, Mancini SJ, Boher JM, Hébert J, Sauvageau G, Vey N, Schwaller J, Hospital MA, Fauriat C, Aurrand-Lions MA
    Blood Adv 2024-07-02 ;

  • See all publications