Research field

Cell Signaling & Protein Dynamics

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Study of how cells perceive and interpret stimuli from their environment and how those signals modify gene expression and the activity of the cell’s regulatory proteins.

Principal Investigators

  • Sébastien Carréno

    Cellular Mechanisms of Morphogenesis during Mitosis and Cell Motility

  • Gregory Emery

    Vesicular Trafficking and Cell Signalling

  • Sylvie Mader

    Molecular Targeting in Breast Cancer Treatment

  • Sylvain Meloche

    Signalling and Cell Growth

  • Philippe P. Roux

    Cell Signaling and Proteomics

  • Matthew Smith

    Cancer Signalling and Structural Biology

  • Marc Therrien

    Intracellular Signalling

  • Pierre Thibault

    Proteomics and Mass Spectrometry

Publications

  • July 25, 2024

    Syngeneic mouse model of YES-driven metastatic and proliferative hepatocellular carcinoma.

    Voisin L, Lapouge M, Saba-El-Leil MK, Gombos M, Javary J, Trinh VQ, Meloche S
    Dis Model Mech 2024-07-25 ;17( 7 ):

  • July 18, 2024

    Ezrin, radixin, and moesin are dispensable for macrophage migration and cellular cortex mechanics.

    Verdys P, Rey Barroso J, Girel A, Vermeil J, Bergert M, Sanchez T, Métais A, Mangeat T, Bellard E, Bigot C, Astarie-Dequeker C, Labrousse A, Girard JP, Maridonneau-Parini I, Vérollet C, Lagarrigue F, Diz-Muñoz A, Heuvingh J, Piel M, du Roure O, Le Cabec V, Carréno S, Poincloux R
    EMBO J 2024-07-18 ;

  • July 15, 2024

    Complex interplay between RAS GTPases and RASSF effectors regulates subcellular localization of YAP.

    Singh S, Bernal Astrain G, Hincapie AM, Goudreault M, Smith M
    EMBO Rep 2024-07-15 ;

  • See all publications