A unique model
IRIC, located in the heart of the Université de Montréal campus, operates according to a unique model in Canada that combines, under one roof, fundamental research activities, a university-level training program and a research maturation team. These generate discoveries that advance knowledge or that can quickly translate into new therapeutic solutions.
-
![]()
Event Scientific Conferences - Fall 2026
September 14—December 13, 2026
IRIC presents the 41st edition of its scientific lecture series—Fall 2026.
-
![]()
News Science at the heart of Summer Interns’ Scientific Day at IRIC!
The 8th IRIC Summer Summer Interns’ Scientific Day once again showcased the talent, creativity, and dedication of our young scientists. The event was organized by the IRIC Office of Academic Affairs in collaboration with summer interns.
-
![]()
News Nearly $2 million in funding for the acquisition of state-of-the-art equipment at IRIC
The Canada Foundation for Innovation (CFI) recently announced the results of its John R. Evans Leaders Fund competition. This program enables universities to attract and retain world-class researchers in Canada by providing them with state-of-the-art infrastructure. The CFI’s funding is supplemented by the Government of Quebec and other partners. Two IRIC projects have been awarded grants through this program.
-
![]()
News The Natural Sciences and Engineering Research Council of Canada Funds Two IRIC Projects
The Natural Sciences and Engineering Research Council of Canada (NSERC) recently awarded its 2026 Discovery Grants. This program aims to support ongoing research programs with long-term goals. Two IRIC projects have been awarded these grants.
-
![]()
News The Canadian Institutes of Health Research Funds Two Projects from Guy Sauvageau’s Laboratory
The Canadian Institutes of Health Research (CIHR) recently awarded grants for the Project program as part of the Spring 2026 competition. Two projects from IRIC’s Molecular Genetics of Stem Cells Research Unit, led by Guy Sauvageau, received funding.
-
![]()
News Ribosomal Dysfunction as an Oncogenic Driver in Certain Leukemias
The team led by Guy Sauvageau, director of IRIC’s Molecular Genetics of Stem Cells Research Unit, has identified a subtype of acute myeloid leukemia (AML) characterized by a significant reduction in the cells’ ability to produce proteins resulting from the loss of several ribosomal genes. This study, which proposes a new conceptual model of leukemogenesis, paves the way for the identification of new biomarkers and a new therapeutic vulnerability. Led by Principal Research Advisor Jean-François Spinella, this work is published in the journal Science Advances.
Latest publications
See all publications-
August 31, 2026 Lysyl oxidase inhibition disrupts mitochondrial homeostasis to create vulnerability to ferroptosis in TNBC.
Saatci O, Ulukan B, Cetin M, Kuasne H, Martinez C, Percin E, Oleinik N, Savoca MT, Nehme A, Hernández-Corchado A, Zavacky E, Sreenivas K, Rezaeian AH, Bethard JR, Anoma JS, Sahin OS, Aguilar-Mahecha A, Buchanan M, Aras M, DeBlois G, Basik M, Hill EG, Ball LE, Rao CN, McInnes C, Riazalhosseini Y, Najafabadi HS, Lemasters JJ, Ogretmen B, Park M, Sahin O
Cell Rep Med 2026-08-31 ;7( 9 ):103015 -
August 28, 2026 The structure of the dopamine D3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology.
Hadas Yardeni E, Kiss DJ, Sanchez J, Shavit K, Szepesi Kovács D, Egyed A, Vogt CD, Gaitonde SA, Glenn J, Canals M, Bouvier M, Newman AH, Lane JR, Keserű GM, Shalev-Benami M
Sci Adv 2026-08-28 ;12( 35 ):eaef7411 -
August 18, 2026 - See all publications