Principal Investigator

Philippe P. Roux

Cell Signaling and Proteomics

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Following a Doctoral degree in Molecular Neuroscience at McGill University, Philippe P. Roux went to Harvard Medical School (USA) for Postdoctoral Fellowship in cancer biology.

In 2006, he joined IRIC as Principal Investigator in the Cell Signaling and Proteomics Research Unit. Promoted to the rank of full Professor in 2018, Philippe Roux teaches in the Department of Pathology and Cell Biology of the Faculty of Medicine at the Université de Montréal. He is also senior Research Fellow of the Fonds de recherche du Québec – Santé. In 2023, Philippe P. Roux succeeds Marc Therrien as Scientific Director of IRIC.

Scientific Director, IRIC

Principal Investigator, Cell Signalling and Proteomics Research Unit, IRIC

Professor, Department of Pathology and Cell Biology, Faculty of Medecine, Université de Montréal

Research unit on cell signalling and proteomics

Marcelle-Coutu Pavilion, 1306-17

Phone (office)
(514) 343-6399
Fax
(514) 343-7780
Email
philippe.roux@umontreal.ca
Apply for a M.Sc. or a Ph.D.

Cell Signaling and Proteomics

Philippe Roux and his team seek to understand the molecular mechanisms by which oncogenes transform a normal cell into a cancerous one. This knowledge is crucial for the discovery of novel therapeutic targets and to decipher the molecular causes of resistance to treatment.

Discover the research unit View the research team

Research topics

Publications

  • June 4, 2024

    Immunotherapeutic targeting of surfaceome heterogeneity in AML.

    Bordeleau ME, Audemard E, Métois A, Theret L, Lisi V, Farah A, Spinella JF, Chagraoui J, Moujaber O, Aubert L, Khakipoor B, Mallinger L, Boivin I, Mayotte N, Hajmirza A, Bonneil E, Béliveau F, Pfammatter S, Feghaly A, Boucher G, Gendron P, Thibault P, Barabé F, Lemieux S, Richard-Carpentier G, Hébert J, Lavallée VP, Roux PP, Sauvageau G
    Cell Rep 2024-06-04 ;43( 6 ):114260

  • March 19, 2024

    14-3-3ζ regulates adipogenesis by modulating chromatin accessibility during the early stages of adipocyte differentiation.

    Rial SA, You Z, Vivoli A, Sean D, Al-Khoury A, Lavoie G, Civelek M, Martinez-Sanchez A, Roux PP, Durcan TM, Lim GE
    bioRxiv 2024-03-19 ;

  • February 15, 2024

    Plakoglobin regulates adipocyte differentiation independently of the Wnt/β-catenin signaling pathway.

    Abou Azar F, Mugabo Y, Yuen S, Del Veliz S, Paré F, Rial SA, Lavoie G, Roux PP, Lim GE
    Biochim Biophys Acta Mol Cell Res 2024-02-15 ;1871( 4 ):119690

  • February 9, 2024

    Identification of RSK substrates using an analog-sensitive kinase approach.

    Lizcano-Perret B, Vertommen D, Herinckx G, Calabrese V, Gatto L, Roux PP, Michiels T
    J Biol Chem 2024-02-09 ;105739

  • See all publications

Awards and distinctions

  • Project Grant - Canadian Institutes of Health Research, 2021-2026

  • Senior Investigator Award, Fonds de recherche du Québec - Santé, 2016-2020

  • GE Healthcare Young Investigator Award, Canadian Society for Molecular Biosciences, 2013

  • Career Development Award, Human Frontier Science Program, 2007-2010

  • Canada Research Chair (tier 2) in Cell Signaling and Proteomics, 2006-2016

  • Postdoctoral Fellowship, Human Frontier Science Program, 2003-2006